专利名称：ANTI-RANKL ANTIBODY
发明人：HONMA, Masashi，本間　雅,SUZUKI, Hiroshi，鈴木　洋史,KARIYA, Yoshiaki，苅谷　嘉
顕,HAYASHI, Madoka，林　円香,IKEBUCHI,
Yuki，池淵　祐樹
申请号：JP2015/054806
申请日：20150220
buchi
公开号：WO2015/125922A1
公开日：
20150827
专利内容由知识产权出版社提供
摘要：The purpose of the present invention is to provide a new therapeutic agent for bone metabolism-related disease. Provided is an anti-RANKL antibody, or a functional fragment thereof, that binds with the RANKL extracellular domain, displays osteoblast-activating capability by crosslinking two or more RANKL trimers, and at the same time, displays mature osteoclast formation-inhibiting capability by inhibiting the binding of RANKL to RANK.
申请人：THE UNIVERSITY OF TOKYO，国立大学法人東京大学
地址：〒1138654 JP,〒1138654 JP
国籍：JP,JP
代理人：THE PATENT CORPORATE BODY ARUGA PATENT OFFICE，特許業務法人アルガ特許事務所
更多信息请下载全文后查看